Fluoride & Remin Study ✓ Peer reviewed

Comparative evaluation of fluoridated, nonfluoridated, and herbal dentifrices with digital oral health intervention on salivary cariogenic microorganisms and alpha-amylase levels in children with severe early childhood caries.

Journal of the Indian Society of Pedodontics and Preventive Dentistry · Sarkar A, Yadav G, Navit S, Saha S, Kalita M, Singh A · 2026-07-01

Researchers compared four types of toothpaste (high-fluoride, low-fluoride, nonfluoride, and herbal) in children with severe early childhood caries and found that high-fluoride dentifrice reduced cavity-causing bacteria most effectively and better modulated salivary alpha-amylase levels.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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