Cold Atmospheric Plasma in Periodontitis: Mechanisms, Antimicrobial and Immunomodulatory Effects, and Therapeutic Potential-A Comprehensive Review.

A comprehensive review examined how cold atmospheric plasma—which produces reactive molecules—might help treat periodontitis by killing bacteria, disrupting biofilms, and modulating immune responses. Preclinical studies showed promising antimicrobial and tissue-repair effects, while limited clinical trials suggested improvements in attachment levels when combined with scaling and root planing, though standardized protocols and long-term safety data remain lacking.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.