Perio & Hygiene Study ✓ Peer reviewed

Periodontitis and metabolic dysfunction-associated steatotic liver disease.

Periodontology 2000 · de Molon RS, de Avila ED, da Silva Barbirato D, Fogacci MF, Shibli JA, Sculean A, Kantarci A · 2026-08-25

A narrative review found consistent evidence of a bidirectional relationship between periodontitis and metabolic dysfunction-associated steatotic liver disease, with shared inflammatory and metabolic pathways involving oral-gut-liver axis mechanisms, and preliminary evidence suggesting periodontal treatment may improve liver outcomes.

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