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Dental Management of Self-Injurious Behavior in Lesch-Nyhan Disease: A Patient- and Caregiver-Reported Outcome Study.

Children (Basel, Switzerland) · Capurro C, Parodi S, Buttiglieri S, Romanelli G, Del Buono C, Laffi N · 2026-07-29

Researchers surveyed patients with Lesch-Nyhan disease to assess how intraoral devices and dental extractions affected self-injurious behaviour involving the mouth. Intraoral devices were more commonly used and well-tolerated, offering perceived reassurance, while extractions provided relief but did not always stop the injurious behaviour.

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