MicroRNAs in periodontal disease: from pathogenic mechanisms and RANKL/OPG regulation to nanoparticle delivery and personalized medicine.

Dysregulated microRNAs in periodontal disease contribute to bone loss and inflammation through altered RANKL/OPG signalling and impaired stem cell development; three miRNAs show promise as non-invasive biomarkers, while nanoparticle-delivered therapies demonstrate preclinical effectiveness but require resolution of delivery and safety challenges.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.