Fluvastatin enhances healing of medication-related osteonecrosis of the jaw (MRONJ) via macrophage polarization in a rat MRONJ-like model.
In a rat model, fluvastatin administered locally to extraction sites improved healing of medication-related osteonecrosis of the jaw induced by zoledronic acid and dexamethasone, appearing to work by shifting macrophage populations toward a tissue-repair phenotype.
A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.
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