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Is C-Terminal Telopeptide Associated With Medication-Related Osteonecrosis of the Jaw Risk Following Extraction in Osteoporosis Patients Treated With Denosumab?

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons · Yu E, Colella A, Sambrook P, Goss A · 2026-08-20

Researchers followed osteoporosis patients on denosumab who underwent tooth extraction, finding that lower bone turnover markers and extracting more teeth were associated with developing jaw osteonecrosis.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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