Special Needs & Medical Study ✓ Peer reviewed

Systematic evaluation of genetic polymorphisms in carcinogen metabolizing enzymes associated with oral potentially malignant disorders progression to oral cancer risk.

Journal of dental sciences · Xu Z, Zhu Y, Shi L, Liu W · 2026-04-01

A systematic review pooled data from multiple studies examining genetic variants in five carcinogen-metabolising enzymes and their association with oral potentially malignant disorder progression to oral cancer. The GSTM1 null genotype showed increased cancer risk, while other tested variants showed no significant association.

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