Other Research Study ✓ Peer reviewed

Spatially resolved transcriptomics identifies epithelial-specific oncogenic signaling networks in ameloblastoma.

Journal of dental sciences · Tseng CH, Yoshimoto S, Hung KF, Lu PH, Wang YP, Chang JY · 2026-07-01

Researchers used spatial transcriptomics to identify 75 dysregulated genes and multiple activated signaling pathways (Wnt/β-catenin, PI3K/AKT, MAPK, Hedgehog) specifically within ameloblastoma tumor epithelial cells, revealing coordinated molecular mechanisms that may guide future therapeutic approaches.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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