Other Research Study ✓ Peer reviewed

Polypharmacy and Self-Reported Tooth Clenching: An Electronic Health Record Analysis.

JDR clinical and translational research · Nguyen P, Marchini L, Greenwood A, Vu G, Zeng E · 2026-09-04

Researchers examined electronic health records from over 14,000 dental patients to identify associations between central nervous system medications and self-reported tooth clenching. SNRIs and use of multiple CNS medications showed increased odds of clenching, whereas SSRIs alone did not.

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