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Sjögren's disease patients with no hyposalivation and with short oral dryness complaints contain more T cells in salivary gland parenchyma.

Rheumatology (Oxford, England) · Yang T, Liefers SC, van der Vegt B, van der Geest KSM, de Leeuw K, Bootsma H, Kroese FGM, Pringle S · 2026-09-01

Researchers found that Sjögren's disease patients without reduced saliva flow and with brief dryness symptoms had higher numbers of CD4+ and CD8+ T cells in salivary gland tissue compared to those with established disease, suggesting T cell infiltration occurs early in the condition.

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