Special Needs & Medical Study ✓ Peer reviewed

[Research progress on the pathogenesis of medication-related osteonecrosis of the jaw based on immune-vascular coupling dysfunction].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · Jiang ZS, Ye L, Cao ZW, Zhao CZ, Zhang N, Liu JY, Pan J · 2026-07-30

Medication-related osteonecrosis of the jaw appears to develop when anti-resorptive drugs disrupt both immune function and blood vessel health, preventing proper repair of bone and soft tissues. The review identifies macrophage dysfunction and vascular damage as key contributors to persistent inflammation and tissue breakdown.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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