Special Needs & Medical Study ✓ Peer reviewed

[Role and mechanism of methyltransferase-like 3 in promoting macrophage NLRP3 inflammatory responses in medication-related osteonecrosis of the jaw].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology · Jiang ZS, Zhao CZ, Pan ZJ, Hu LR, Zhang N, Pan J · 2026-07-30

Researchers used single-cell analysis to show that METTL3, an epigenetic modifier, promotes inflammatory responses in macrophages via NLRP3 activation in bisphosphonate-related jaw osteonecrosis, suggesting it as a potential therapeutic target.

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