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Pharmacological effects of PTH1R agonists on jaw bone fracture, periodontitis, orthodontic treatment and MRONJ: a view from dosing regimen settings.

Journal of oral biosciences · Nakanishi-Kimura A, Tsuji N, Scheller EL, Iimura T · 2026-07-26

PTH1R agonists (teriparatide and abaloparatide) show potential in dental applications including jaw bone regeneration, orthodontics, and periodontitis treatment, but mandibular bone may require higher doses and longer treatment periods than other skeletal sites.

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