Perio & Hygiene Meta-analysis ✓ Peer reviewed

Efficacy of omega-3 fatty acids supplementation as an adjunct to nonsurgical periodontal therapy in periodontitis: a systematic review and meta-analysis of randomized controlled trials.

Revista cientifica odontologica (Universidad Cientifica del Sur) · Irmawati A, Muhammad Ridho F, Labib R, Alfatah R, Maulidina Cahyani S · 2026-07-10

A meta-analysis of nine randomised controlled trials found that omega-3 fatty acid supplements combined with scaling and root planing produced greater reductions in probing pocket depth and gains in clinical attachment level compared with scaling and root planing alone, though evidence quality was low and heterogeneity was substantial.

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