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Efficacy and safety of intraseptal and periodontal ligament anaesthesia for extraction of upper lateral incisors and lower first premolars in patients with type 2 diabetes mellitus.

Frontiers in oral health · Biocanin V, Brkovic B, Stevanovic M, Vasiljevic M, Biocanin M, Stojic D · 2026-08-24

Researchers compared intraseptal and periodontal ligament anaesthesia using a computer-controlled delivery system for tooth extractions in patients with controlled type 2 diabetes. Intraseptal anaesthesia provided longer-lasting and wider anesthetic coverage than periodontal ligament anaesthesia, with both techniques proving safe and effective without significant cardiovascular changes.

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