Special Needs & Medical Case report ✓ Peer reviewed

Management of oral stomatitis associated with BRAFi-MEKi therapy using intralesional corticosteroid and local anesthetic: a case report.

Einstein (Sao Paulo, Brazil) · Oliveira MCQ, Cuzzullin MC, Miranda VL, Gomes APAP, Marcassa JC, Vargas PA, Roza ALOC, Rocha AC, Santos-Silva AR, Prado-Ribeiro AC, Souza JGS, Vechiato-Filho AJ · 2026-09-07

A patient developed a fibrinopurulent ulcer with hyperplasia on her tongue after starting combined BRAF and MEK inhibitor therapy for melanoma; intralesional corticosteroid and local anesthetic injection followed by topical corticosteroid achieved complete healing.

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