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Therapeutic effects of a synthetic glabridin derivative on metabolic immuno-regulation and salivary gland functional restoration in experimental Sjögren's syndrome.

Experimental & molecular medicine · Park JS, Kang HY, Jeong HY, Choi J, Cho SH, Lee SB, Cho ML, Park SH · 2026-07-21

A synthetic glabridin derivative called HGR4113 reduced salivary gland inflammation and improved saliva production in mice with Sjögren's syndrome-like disease by suppressing immune cell activity and promoting tissue repair.

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