Other Research Study ✓ Peer reviewed

Effect of self-activating phthalocyanine gel on palatal donor site healing, inflammatory biomarkers, somatosensory and patient-centered outcomes: a randomized split-mouth clinical trial.

Clinical oral investigations · Santos CA, Cavallieri RS, Sementille MC, Dionísio TJ, Salbego RS, Damante CA, Bonjardim LR, Ragghianti Zangrando MS · 2026-09-12

A split-mouth trial compared phthalocyanine gel versus placebo on palatal donor sites after connective tissue graft harvesting. Both treatments achieved similar healing, though the active gel showed reduced residual remodeling and increased anti-inflammatory markers.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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