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Comparative Evaluation of Salivary Zinc Finger E-Box Binding Homeobox 1 (ZEB1) Levels in Healthy Individuals, Periodontitis, and Oral Squamous Cell Carcinoma Patients: A Cross-Sectional Study.

Cureus · Shikalgar SA, Zope SA, Suragimath G, Varma S, Kale AV, Gudur RA · 2026-08-11

Salivary levels of ZEB1, a protein involved in cell transformation, were significantly higher in patients with periodontitis and oral cancer compared to healthy individuals, with the highest levels in cancer patients, suggesting it may serve as a non-invasive indicator of these oral diseases.

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