Dental caries associated with medications for opioid use disorder: drug effects, formulation factors, or both?
Buprenorphine and methadone medications for opioid use disorder are linked to increased dental caries risk through multiple mechanisms: acidic ingredients in transmucosal formulations lower mouth pH, while the drugs themselves may reduce saliva production and allow drug accumulation in oral tissues. Naltrexone carries lower caries risk, suggesting both formulation and drug properties contribute to dental complications.
A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.
Read the full study at the sourceRelated CPD from Vital Pulp
Once and for All: Does Flossing Prevent Caries?
What the evidence actually says — an honest, cited look at flossing, caries and gum health
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