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Effects of Fluoride and 8:2 FTOH on β-Cell Calcium Signaling and Insulin Homeostasis: An Exploratory Study.

Metabolites · Trevizol JS, Okamoto M, Yamashita S, Kuriki N, Brueckner S, Shindo S, Kawai T, Damião REV, Dionizio A, Buzalaf MAR, Suzuki M · 2026-07-04

Researchers exposed pancreatic cells to fluoride and a PFAS chemical, finding both altered calcium signaling in insulin-producing cells through different dose-dependent mechanisms and affected related metabolic pathways in mouse pancreases.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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