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Mechanobiology and Molecular Regulation of Periodontal Tissue Remodeling During Orthodontic Tooth Movement: From Periodontal Phenotype to Precision Orthodontics-A Narrative Review.

International journal of molecular sciences · Górski B, Kalina E, Derwich M · 2026-08-28

Orthodontic outcomes depend on individual biological responses to tooth movement, not just biomechanical forces. This review examines molecular pathways and biomarkers influencing periodontal remodeling, and explores how advanced imaging and artificial intelligence could support personalized treatment planning to reduce complications.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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