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Clinical and Biochemical Effects of Repeated Injectable Platelet-Rich Fibrin Application in Periodontitis Treatment: A Randomized Controlled Clinical Trial.

International journal of dental hygiene · Ulu Emir B, Özcan E, Avcı E · 2026-09-14

Researchers tested whether injecting platelet-rich fibrin into periodontal pockets alongside scaling and root planing improved outcomes compared to saline alone. The fibrin-treated sites showed better attachment and lower inflammatory markers at 3 months, though pocket depth improvements were not significantly different.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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