Perio & Hygiene Study ✓ Peer reviewed

Assessment of the Association of Periodontitis and Diabetes Mellitus with Alzheimer's Disease in a Mouse Model.

International journal of molecular sciences · Nakahara M, Kataoka K, Maruyama T, Nurhamim M, Zhang Y, Fukuhara D, Uchida-Fukuhara Y, Islam MM, Morita M, Saito T, Ekuni D · 2026-08-23

Researchers induced periodontitis and diabetes in Alzheimer's disease model mice and found that the combined conditions impaired memory and reduced expression of a gene (Neurod1) in the brain, suggesting a shared regulatory pathway involving a specific microRNA.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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