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Association between DNA methylation-based aging clocks and periodontitis in aged adults: results from NHANES 1999-2002.

Epigenomics · Cai Y, Cui Z, Shen Y, Lin L, Yu W, Shen Y, Jiang B, Lu E, Jin M · 2026-09-15

Researchers examined whether DNA methylation-based aging clocks predict periodontitis risk in adults aged 50+ using NHANES data, finding that higher epigenetic aging measures (particularly PhenoAge and GrimAge2) were associated with increased odds of periodontitis.

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