Paediatric & MIH Study ✓ Peer reviewed

Developmental ecology of the infant oral ecosystem: a framework for early childhood caries.

Frontiers in oral health · Matera M, Besostri A, Cavecchia I, Illiceto MT, Lenzi MB, D'Ambrosio T, Baldassarre ME, Biagioli V · 2026-09-04

Researchers propose that early childhood caries results from disrupted development of the infant oral ecosystem due to interconnected maternal, nutritional, immune, and microbial influences during pregnancy and the first 1,000 days of life, rather than primarily from sugar and acidogenic bacteria alone.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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