Paediatric & MIH Study ✓ Peer reviewed

The efficacy of transdermal melatonin in dental anxiety in children: a randomised placebo-controlled clinical trial.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · Wahba N, Nagi BM, El-Baraky IA, El-Motayam AK · 2026-09-18

Transdermal melatonin patches did not reduce self-reported anxiety in children undergoing dental treatment, though they showed modest cardioprotective effects by blunting the heart rate and blood pressure rise typically associated with local anaesthetic injection.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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