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Comparative efficacy of locally delivered 1.2% rosuvastatin and 1.2% simvastatin gel as an adjunct to non-surgical periodontal therapy in chronic periodontitis: a clinical and microbiological assay.

The Saudi dental journal · Rajaram H, Bindu GH, Rani KR, Shah MA, Kamath V · 2026-09-23

Researchers compared locally delivered rosuvastatin and simvastatin gels alongside scaling and root planing for treating chronic periodontitis pockets. Both statin gels significantly improved clinical and microbiological outcomes compared to placebo, with simvastatin showing slightly greater improvements, though the difference was not statistically significant.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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