Perio & Hygiene Study ✓ Peer reviewed

Beyond vitamin D: integrating nuclear receptor signaling networks in periodontal health and disease.

Frontiers in physiology · Chen Y, Guan L, Li Q, Chai Y, Gao J · 2026-09-29

This review examines four nuclear receptor signaling pathways (VDR, PPAR-γ, FXR, and RXR-α) implicated in periodontal disease progression, identifying knowledge gaps and proposing a network-based research framework to advance understanding of their integrated roles in periodontal health and disease.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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