Perio & Hygiene Study ✓ Peer reviewed

Comparative evaluation of guava leaf extract and chlorhexidine mouthwash in plaque-induced gingivitis: A clinical and computational approach.

Journal of oral biology and craniofacial research · Praveena S, Kumar T, Sivasamy S, Chaly PE · 2026-11-01

A randomised controlled trial compared guava leaf extract mouthwash with chlorhexidine as adjuncts to professional scaling for plaque-induced gingivitis. Both mouthwashes similarly reduced plaque and gingival scores over 28 days, with computational analysis suggesting guava's active compounds may be effective against *P. gingivalis*.

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