Perio & Hygiene Study ✓ Peer reviewed

Mertk drives alveolar bone loss in experimental periodontitis associated with altered neutrophil function and osteoclast recruitment.

Journal of periodontology · Mazzara N, Martin K, Dabaja R, Redmond J, Maglaras V, Mianecki M, Ashekian H, Decker JT, Decker AM · 2026-10-12

Mertk-deficient mice experienced less alveolar bone loss during induced periodontitis than normal mice, associated with reduced neutrophil reactive oxygen species production, decreased neutrophil degranulation, and fewer osteoclasts in periodontal tissues.

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