Perio & Hygiene Review ✓ Peer reviewed

Does clinical improvement indicate biological resolution after periodontal therapy? An evidence-informed narrative review.

Odontology · Bıçakçıoğlu HA · 2026-10-20

Clinical improvement following periodontal therapy doesn't necessarily indicate complete biological healing, as some treated sites retain abnormal microbial communities and inflammatory markers despite improved clinical appearance. The review suggests multiple biological pathways may impair tissue recovery, but evidence that these mechanisms predict recurrence independently of existing clinical indicators remains unclear.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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