Sesamin suppresses high glucose-induced cyclooxygenase-2 and prostaglandin E(2) production through Toll-like receptor 2-dependent oxidative stress in human gingival fibroblasts.
Sesamin, a compound from sesame, reduced inflammatory markers and oxidative stress produced by gingival fibroblasts exposed to high glucose levels by suppressing a specific immune signaling pathway involved in diabetes-related periodontal inflammation.
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