Special Needs & Medical Observational ✓ Peer reviewed

Enhanced salivary correlation between Streptococcus mutans and herpes simplex virus-1 in oral squamous cell carcinoma: a case-control study.

BMC oral health · Kim TL, Shin CG, Oh SY, Lee HJ, Kwak S, Kwon TG, Kim JW, Choi SY, Hong SH · 2026-08-03

Salivary levels of *Streptococcus mutans* and herpes simplex virus-1 were higher in oral squamous cell carcinoma patients than controls, with a much stronger correlation between these two organisms in cancer patients—particularly among those with alcohol or smoking histories.

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