Airways & Growth Review ✓ Peer reviewed

Orthodontic and Craniofacial Skeletal Alterations in Individuals With Thalassemia: A Scoping Review.

Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · da Silva LC, Santos DBDN, de Arruda JAA, Abreu LG, Drumond VZ, Cruz TCSDS, Nojima MDCG, de Andrade BAB, Tenório JR · 2026-09-01

Researchers reviewed 26 studies involving 2,353 people with thalassemia and identified characteristic skeletal patterns including mandibular retrusion, maxillary protrusion, and Class II malocclusion, with severity linked to anemia severity and transfusion delays.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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