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Targeting Fibrin Deposit Alleviates Periodontitis via Neutrophil Modulation

Journal of Dental Research · B. Zhang, J. Wang, T. Wang, Z. Zong, X. Liu, Z. Xu, H. Zhang, Y. Wang, J. Feng, D. Wang, S. Wang, Y. Zhang, X. Yang, W. Zhao, J. Li, S. Ge · 2026-08-31

Researchers developed a fibrin-targeting hydrogel delivery system that reduces neutrophil overactivation and inflammatory markers in periodontitis, while promoting bone regeneration and reducing alveolar bone loss in a mouse model.

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