Perio & Hygiene Randomised controlled trial ✓ Peer reviewed

Evaluation of Dyclonine Hydrochloride Mucilage for Pain Control in Plaque Control-Oriented Periodontal Therapy: A Double-Blind Randomised Clinical Trial.

International journal of dental hygiene · Yi Z, Hangfan Z, Rongli H, Zixiang W, Xiangyuan C, Jiantang Y, Kun Y, Fuhua Y, Song G · 2026-08-30

Researchers compared dyclonine hydrochloride mucilage to placebo during guided biofilm therapy in a split-mouth study, finding that the active treatment significantly reduced pain across scaling, air polishing, and probing procedures, with greater benefit observed in anxious patients.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

Read the full study at the source
The Recall — the month's most significant new dental research, summarised. Free.
Browse The Recall