Perio & Hygiene Meta-analysis ✓ Peer reviewed

Association between periodontal disease severity and the risk of medication-related osteonecrosis of the jaw: a systematic review and meta-analysis by the Korean Academy of Periodontology.

Journal of periodontal & implant science · Lee JH, Kim YJ, Song YW, Kim S, Chung JH, Seol YJ, Lee HJ · 2026-08-01

A systematic review of eight studies found that patients with periodontal disease had approximately three times higher risk of developing medication-related osteonecrosis of the jaw compared to those without periodontal disease, with greater risk associated with more severe periodontal breakdown.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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