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Periodontitis Exacerbates Insulin Resistance via Gut Barrier Dysfunction and TLR4/NF-κB Activation.

International dental journal · Jiang L, Huang Y, Zhang S, Li X, Mo F, Huang C, Tao R · 2026-09-02

Researchers found that in diabetic mice, periodontitis worsened insulin resistance and glucose control by damaging the intestinal barrier, reducing protective mucus and tight junction proteins, and triggering inflammatory immune pathways in the gut.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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