Paediatric & MIH Randomised controlled trial ✓ Peer reviewed

Efficacy of ethyl chloride topical anesthesia application on pain perception during intra-oral injections in children compared to benzocaine gel-a single-blind randomized controlled trial.

Frontiers in dental medicine · Abdelrahman N, Al Halabi M, Kowash M, Hussein I, Salami A · 2026-08-19

Children aged 7–10 years receiving dental injections showed similar reductions in pain and stress responses whether treated with ethyl chloride spray or benzocaine gel, with neither topical anesthetic demonstrating superiority over the other.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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