Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo.
Researchers transplanted gingival stem cells into rabbit gingiva during orthodontic tooth movement and found that hypoxic-preconditioned cells produced faster tooth movement, higher bone-forming protein expression, and lower inflammatory markers compared to normoxic cells or controls.
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