Airways & Growth Study ✓ Peer reviewed

Mesenchymal stem cells derived from gingiva normoxic or hypoxic-preconditioning allogenous transplantation affect orthodontic tooth movement in vivo.

Journal of dental sciences · Nugraha AP, Hong G, Yang K, Narmada IB, Rantam FA, Ernawati DS, Ardani IGAW, Pramusita A, Putranti NAR, Fadzila NDR, Aurora AZS, Farizaldi RI, Luthfi M, Situmorang PC, Riawan W, Tanimoto K · 2026-07-01

Researchers transplanted gingival stem cells into rabbit gingiva during orthodontic tooth movement and found that hypoxic-preconditioned cells produced faster tooth movement, higher bone-forming protein expression, and lower inflammatory markers compared to normoxic cells or controls.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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