Perio & Hygiene Study ✓ Peer reviewed

Comparative Diagnostic Performance of Oral Microbial Habitats for Periodontitis.

Journal of dental research · Tomás I, Suárez-Rodríguez B, Blanco-Pintos T, Sánchez-Barco A, Alonso-Sampedro M, Carreira MJ, Regueira-Iglesias A, Balsa-Castro C · 2026-09-07

Researchers analysed oral microbial samples from over 2,000 adults to evaluate which oral habitat best diagnoses periodontitis. Saliva and supragingival plaque outperformed subgingival samples, with saliva achieving the highest diagnostic accuracy and clinical utility using machine-learning analysis of specific bacterial signatures.

A plain-English summary of the study's own findings — we don't add our own claims or interpretation. Read the full paper for the complete methods and results, and apply your own clinical judgement.

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